What RNs earn in St. Louis
Registered nurses in the St. Louis, MO-IL metro earn a median of $83,180 a year, 15% below the national RN median of $97,550. The middle half of RNs here earn between $77,410 and $100,230, so experience, specialty and shift differentials can move you a long way inside that range. Among the 60 metro markets The RN Network tracks, St. Louis ranks #51 for median RN pay.
| Role | Median | Typical range |
|---|---|---|
| Registered Nurse | $83,180 | $77,410 – $100,230 |
| Nurse Practitioner | $131,580 | $127,460 – $154,500 |
| Nurse Anesthetist (CRNA) | $232,300 | $214,990 – $313,980 |
| Nurse Midwife | $133,330 | $125,540 – $152,120 |
Powered by RN Workforce Insights™ · 2025 annual pay. Typical range is the 25th to 75th percentile.
Cost of living and the St. Louis nursing market
Pay only tells half the story. A two-bedroom apartment at fair market rent runs about $1,218 a month in St. Louis, which is roughly 18% of a median RN salary before taxes. That leaves RNs here more room in the budget than in most big nursing markets.
About 35,200 RNs work in this metro, the #18 largest RN workforce of the markets we track. The RN Network directory lists 139 healthcare employers in Saint Louis, St. Louis and St Louis, including 46 behavioral health facilities, 37 long-term care facilities, 25 dialysis centers and 17 outpatient surgery centers.
Hospitals hiring nurses in St. Louis
Every hospital below has its own page with pay context, nearby openings and a direct line to its careers site.
Nursing jobs in St. Louis
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Career advice for St. Louis nurses
Watch the latest episode of Nursing Matters, the show that helps nurses find the right job, land the offer and grow their careers.
You Passed the NCLEX. Can You Lose This License? Nursing Matters Episode 102626
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Happy Medical-Surgical Nurses Week, which the Academy of Medical-Surgical Nurses celebrates November 1 through 7 and which opens today.
Read the article →Common questions about nursing in St. Louis
How much do registered nurses make in St. Louis?
The median RN salary in the St. Louis, MO-IL metro is $83,180 a year, and the middle half of RNs earn between $77,410 and $100,230.
What do nurse practitioners earn in St. Louis?
Nurse practitioners in the St. Louis metro earn a median of $131,580 a year.
Can a nurse afford to live in St. Louis?
A two-bedroom apartment at fair market rent costs about $1,218 a month in St. Louis, roughly 18% of a median RN salary before taxes.
Which hospitals hire nurses in St. Louis?
Hospitals in the St. Louis area include Missouri Baptist Medical Center, St Louis-John Cochran VA Medical Center, Barnes Jewish Hospital, Christian Hospital Northeast, Mercy Hospital St Louis. See the full list in The RN Network facility directory.
How do I find a nursing job in St. Louis?
Browse current Missouri openings on The RN Network job board, claim your free Talent Agent profile so employers hiring in St. Louis can find you, and compare pay using the Missouri salary guide.