Average registered nurse compensation in South Dakota across seven career stages — from new grad RN to Chief Nursing Officer. Updated 2026 benchmarks to help you negotiate, plan, and grow.
RN Salary by Role in South Dakota
Nurses in South Dakota earn below the national median, with staff RN pay averaging about $64,000 annually, a figure that goes further given the state's lower cost of living.
The earnings curve is significant across a nursing career in South Dakota. Entry-level new grad RNs generally start near $47,000, while experienced specialty nurses in high-acuity areas (ICU, ER, OR) average closer to $73,000. Leadership tracks open up further upside: nurse managers average around $81,000, directors of nursing near $94,000, and CNOs can reach $111,000. Advanced practice nurses (NPs, CNSs, CRNAs, and CNMs) in South Dakota report average compensation around $81,000.
South Dakota is a member of the Nurse Licensure Compact, so a multistate RN or LPN license issued here is valid for practice in other compact states — useful for travel nursing, telehealth, or relocating without re-licensing.
South Dakota's lower wages are often paired with a lower cost of living, which can narrow the real-world gap compared to higher-paying states.
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